<ul> <li>Job title Director, U.S. Head of Translational Pharmacokinetics & Pharmacodynamics Modeling </li><li>Function Discovery & Pre-Clinical/Clinical Development </li><li>Sub function Pharmacokinetics & Pharmacometrics </li><li>Category Director, Pharmacokinetics & Pharmacometrics (PL9) </li><li>Location Spring House / San Diego / United States of America </li><li>Date posted Apr 25 2025 </li><li>Requisition number R-009936 </li><li>Work pattern Hybrid Work </li></ul> <p>This job posting is anticipated to close on May 02 2025. We may however extend this time period, in which case the posting will remain available on www.careers.jnj.com to accept additional applications.</p> <p>Description</p> <p>At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com</p> <p>Job Function:</p> <p>Discovery & Pre-Clinical/Clinical Development</p> <p>Job Sub Function:</p> <p>Pharmacokinetics & Pharmacometrics</p> <p>Job Category:</p> <p>People Leader</p> <p>All Job Posting Locations:</p> <p>San Diego, California, United States of America, Spring House, Pennsylvania, United States of America</p> <p>Job Description:</p> <p>About Innovative Medicine</p> <p>Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.</p> <p>Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.</p> <p>Learn more at https://www.jnj.com/innovative-medicine</p> <p>We are searching for the best talent for a Director, U.S. Head of Translational Pharmacokinetics & Pharmacodynamics Modeling to be located in Spring House, PA or La Jolla, CA.</p> <p>Purpose: Understanding pharmacokinetics, pharmacodynamics, and predicting efficacious doses is a critical component of nearly every program in R&D and has been an area of increasing focus across the discovery portfolio. This technically challenging area requires multi-disciplinary expertise and excellent communication skills. We are seeking a dynamic leader who can mentor and guide teams in this high-profile role within the organization.</p> <p>You will be responsible for:</p> <ul> <li> <p>Providing technical expertise and guidance to the team in pharmacokinetic and pharmacodynamic (PK/PD) modeling across all therapeutic areas and modalities in the pipeline.</p> </li><li> <p>Collaborating closely with discovery teams to set overall program PK/PD and dose prediction strategies to ensure efficient generation of key data while minimizing animal use (3Rs).</p> </li><li> <p>Assigning team members to projects (both internal discovery projects and due diligence reviews) based on a combination of expertise, availability, co-location with other project leads, and individual development opportunities.</p> </li><li> <p>Providing strategic direction for the group, identifying additional opportunities where advanced PK and PD modeling strategies can improve R&D effectiveness.</p> </li><li> <p>Providing critical input to due diligence reviews of potential in-licensing and acquisition opportunities.</p> </li><li> <p>Mentoring, training, recruiting, and hiring of team members.</p> </li><li> <p>Maintaining continuity of projects as they move through early development via ongoing communication/collaboration with partners in clinical pharmacology, clinical development, and other members of compound development teams.</p> </li></ul> <p>Qualifications / Requirements:</p> <p>Education:</p> <ul> <li>A minimum of a Bachelor's degree is required. An advanced degree is preferred. </li></ul> <p>Experience & Skills:</p> <ul> <li> <p>10+ years of relevant experience is required.</p> </li><li> <p>Strong familiarity with principles of pharmacokinetics and pharmacodynamics and expertise in use of modeling software for PK and PK/PD analyses is required.</p> </li><li> <p>Experience working across multiple therapeutic areas and multiple drug modalities is required.</p> </li><li> <p>Experience with external innovation, due diligence reviews and onboarding/integration into the portfolio is required.</p> </li><li> <p>Experience using multiple modeling software applications (e.g., R, Monolix, Matlab, NONMEM, Python) is preferred.</p> </li></ul> <p>The anticipated base pay range for this position is $160,000 to $276,000.</p> <p>The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation's performance over a calendar/performance year. Bonuses are awarded at the Company's discretion on an individual basis.</p> <ul> <li> <p>Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.</p> </li><li> <p>Employees may be eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)).</p> </li><li> <p>This position is eligible to participate in the Company's long-term incentive program.</p> </li><li> <p>Employees are eligible for the following time off benefits:</p> </li><li> <p>Vacation - up to 120 hours per calendar year</p> </li><li> <p>Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington - up to 56 hours per calendar year</p> </li><li> <p>Holiday pay, including Floating Holidays - up to 13 days per calendar year of Work, Personal and Family Time - up to 40 hours per calendar year</p> </li><li> <p>Additional information can be found through the link below. https://www.careers.jnj.com/employee-benefits</p> </li></ul> <p>The compensation and benefits information set forth in this posting applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market.</p> <p>This job posting is anticipated to close on 05/02/2025. The Company may however extend this time-period, in which case the posting will remain available on https://www.careers.jnj.com to accept additional applications.</p> <p>Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.</p> <p>Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (ra-employeehealthsup@its.jnj.com) or contact AskGS to be directed to your accommodation resource.</p> <p>An internal pre-identified candidate for consideration has been identified. However, all applications will be considered.</p> <p>The anticipated base pay range for this position is :</p> <p>The anticipated base pay range for this position is $160,000 to $276,000.</p> <p>Additional Description for Pay Transparency:</p>