<ul> <li>Job title Senior Scientist, Cell Line Development </li><li>Function Discovery & Pre-Clinical/Clinical Development </li><li>Sub function Biological Research </li><li>Category Senior Scientist, Biological Research (ST6) </li><li>Location Spring House / United States of America </li><li>Date posted Apr 23 2025 </li><li>Requisition number R-008289 </li><li>Work pattern Fully Onsite </li></ul> <p>This job posting is anticipated to close on May 06 2025. We may however extend this time period, in which case the posting will remain available on www.careers.jnj.com to accept additional applications.</p> <p>Description</p> <p>At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com</p> <p>Job Function:</p> <p>Discovery & Pre-Clinical/Clinical Development</p> <p>Job Sub Function:</p> <p>Biological Research</p> <p>Job Category:</p> <p>Scientific/Technology</p> <p>All Job Posting Locations:</p> <p>Spring House, Pennsylvania, United States of America</p> <p>Job Description:</p> <p>About Innovative Medicine</p> <p>Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.</p> <p>Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.</p> <p>Learn more at https://www.jnj.com/innovative-medicine</p> <p>We are searching for the best talent for Senior Scientist, Cell Line Development in Spring House, PA.</p> <p>Purpose: The Therapeutics Development & Supply department of Johnson & Johnson Innovative Medicine is seeking an ambitious Senior Scientist to join the Cell Line Development group located in Spring House, PA. Johnson & Johnson Innovative Medicine discovers and develops novel solutions to support the unmet medical needs in oncology, immunology, and neuroscience disease areas. Our group specifically generates cell lines that produce large molecule therapeutics in support of the fast-growing pipeline for these various therapeutic areas.</p> <p>As a member of the cell line development team, the candidate will play a crucial role in advancing technology for the next generation of biologics production cell lines. They will plan and execute experiments to overcome limitations of current protein expression systems, focusing on cellular pathways to enhance the quantity and quality of therapeutic proteins.</p> <p>You will be responsible for:</p> <ul> <li>Developing new and innovative technologies for next generation mammalian cell lines secreting complex proteins </li><li>Cell culture development for all protein therapeutics </li><li>Evaluating and implementing cutting-edge technologies in cell biology, molecular biology, genome editing or equipment to improve protein yields and shorten timelines. </li><li>Participating in projects from Lead Optimization to New Molecular Entity declaration within a cross-functional environment </li></ul> <p>In addition to supporting improved Manufacturing Cell Line Development, the candidate will play a key role in liaising with Discovery, Analytical Sciences and Cell Culture Teams for increasing yields and quality of biotherapeutic proteins.</p> <p>Qualifications / Requirements:</p> <p>Education:</p> <ul> <li>Minimum of a Master's Degree in Cell Biology, Molecular Biology, or related scientific field is required. PhD highly preferred. </li></ul> <p>Experience/Skills:</p> <ul> <li>A minimum of 5 years of experience in cell culture, protein expression is required. </li><li>Experience in evaluating, constructing and optimizing biosynthetic pathways utilizing cutting-edge genomics, transcriptomics, protein engineering, and gene editing tools is required. </li><li>Expertise in developing assays for screening of cell lines with high specific and volumetric productivity is required. </li><li>Proven track record of versatility in cell engineering & cell line development is required. </li><li>Ability to work in a matrix environment and connect with different functional groups and people in multiple levels. </li><li>Excellent verbal and written communication skills. </li><li>Experience with maintaining detailed records of work, timely documentation in laboratory notebooks and ability to clearly and concisely present research findings </li><li>Our highly dynamic environment requires you to have a strong work ethic, expect change, and be creative. </li></ul> <p>Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.</p> <p>Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (ra-employeehealthsup@its.jnj.com) or contact AskGS to be directed to your accommodation resource.</p> <p>#LI-Onsite</p>